A postprophase topoisomerase II-dependent chromatid core separation step in the formation of metaphase chromosomes.
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چکیده
منابع مشابه
A postprophase topoisomerase II-dependent chromatid core separation step in the formation of metaphase chromosomes
Metaphase chromatids are believed to consist of loops of chromatin anchored to a central scaffold, of which a major component is the decatenatory enzyme DNA topoisomerase II. Silver impregnation selectively stains an axial element of metaphase and anaphase chromatids; but we find that in earlier stages of mitosis, silver staining reveals an initially single, folded midline structure, which sepa...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1995
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.131.1.7